Mechanisms of action of methotrexate

Immunopharmacology. 2000 May;47(2-3):247-57. doi: 10.1016/s0162-3109(00)00189-2.

Authors

L Genestier¹, R Paillot, L Quemeneur, K Izeradjene, J P Revillard

Affiliation

¹ Laboratory of Immunopharmacology, Institut National de la Santé et de la Recherche Médicale U503, Claude Bernard University, Hopital E. Herriot, Pav. P, 5 Place d'Arsonval 69437, Cedex 03, Lyon, France.

PMID: 10878292
DOI: 10.1016/s0162-3109(00)00189-2

No abstract available

Publication types

Review

MeSH terms

Animals
Anti-Inflammatory Agents, Non-Steroidal / metabolism
Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Apoptosis / drug effects
Apoptosis / physiology
Arthritis, Rheumatoid / drug therapy*
Humans
Immunosuppressive Agents / metabolism
Immunosuppressive Agents / pharmacology*
Immunosuppressive Agents / therapeutic use
Methotrexate / metabolism
Methotrexate / pharmacology*
Methotrexate / therapeutic use
Purine Nucleotides / biosynthesis*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Immunosuppressive Agents
Purine Nucleotides
Methotrexate