A role for Wnts in morpho-genesis and tissue polarity

Nat Cell Biol. 2000 Jul;2(7):E124-5. doi: 10.1038/35017136.

Abstract

Recent studies have shown that secreted Wnt proteins control morphogenetic movements in fish and frog embryos. The analysis of Dishevelled, a cytoplasmic mediator of Wnt signalling, reveals unexpected similarity between gastrulation in vertebrates and polarization of cells in Drosophila epithelia.

Publication types

  • News

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Animals
  • Body Patterning*
  • Cell Lineage
  • Cell Polarity*
  • Dishevelled Proteins
  • Drosophila Proteins
  • Drosophila melanogaster / cytology
  • Drosophila melanogaster / embryology*
  • Drosophila melanogaster / enzymology
  • Drosophila melanogaster / metabolism
  • Gastrula / cytology
  • Gastrula / metabolism
  • Phosphoproteins / metabolism*
  • Proto-Oncogene Proteins / metabolism*
  • Signal Transduction
  • Wnt Proteins
  • Zebrafish Proteins*

Substances

  • Adaptor Proteins, Signal Transducing
  • Dishevelled Proteins
  • Drosophila Proteins
  • Phosphoproteins
  • Proto-Oncogene Proteins
  • Wnt Proteins
  • Zebrafish Proteins
  • dsh protein, Drosophila