Primary lumbosacral Wilms tumour associated with occult spinal dysraphism

Virchows Arch. 2000 May;436(5):502-5. doi: 10.1007/s004280050480.


A 4-year-old child presenting with sudden-onset paraplegia and a sacral tumour in association with spina bifida occulta is reported. There were no stigmata of spinal dysraphism at birth. Imaging studies confirmed a sacral tumour with extradural extension up to T10 and spinal dysraphism. The histological features of the extradural and sacral components of the tumour were consistent with a Wilms tumour. The differential diagnosis included a primary sacral teratoma containing Wilms tumour elements or a primary extrarenal Wilms tumour arising in association with a spinal dysraphism. There was no clinical response to chemotherapy or radiotherapy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Sacrum / pathology*
  • Sacrum / surgery
  • Spinal Dysraphism / complications
  • Spinal Dysraphism / pathology*
  • Spinal Dysraphism / surgery
  • Spinal Neoplasms / complications
  • Spinal Neoplasms / pathology*
  • Spinal Neoplasms / surgery
  • Teratoma / complications
  • Teratoma / pathology*
  • Teratoma / surgery
  • Wilms Tumor / complications
  • Wilms Tumor / pathology*
  • Wilms Tumor / surgery