Detection of thrombosis in the portal venous system: comparison of contrast-enhanced MR angiography with intraarterial digital subtraction angiography

Radiology. 2000 Jul;216(1):86-92. doi: 10.1148/radiology.216.1.r00jl2386.

Abstract

Purpose: To determine whether intraarterial digital subtraction angiography (DSA) can be replaced by contrast material-enhanced magnetic resonance (MR) angiography in the assessment of patency or thrombosis of the portal venous system in patients with portal hypertension.

Materials and methods: Thirty-six patients with portal hypertension underwent contrast-enhanced MR angiography and intraarterial DSA for assessment of the portal venous system. The images were evaluated for vessel patency or thrombosis of the portal, splenic, or superior mesenteric vein.

Results: Of the 101 vessels evaluated, 42 were thrombosed. Overall sensitivity, specificity, and accuracy for the detection of thrombosis were 100%, 98%, and 99%, respectively, for MR angiography and 91%, 100%, and 96%, respectively, for DSA; differences between the imaging methods were not statistically significant. Only in four patients with six vessels (6%) were there discordant findings between MR angiography and DSA.

Conclusion: Noninvasive contrast-enhanced MR angiography has the potential to replace intraarterial DSA as the standard method to assess the whole portal venous system.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Angiography, Digital Subtraction*
  • Contrast Media*
  • Female
  • Gadolinium DTPA*
  • Humans
  • Hypertension, Portal / etiology
  • Magnetic Resonance Angiography*
  • Male
  • Mesenteric Vascular Occlusion / diagnosis
  • Mesenteric Vascular Occlusion / diagnostic imaging
  • Mesenteric Veins / diagnostic imaging
  • Mesenteric Veins / pathology
  • Middle Aged
  • Portal Vein* / diagnostic imaging
  • Portal Vein* / pathology
  • Predictive Value of Tests
  • Retrospective Studies
  • Sensitivity and Specificity
  • Splenic Vein / diagnostic imaging
  • Splenic Vein / pathology
  • Venous Thrombosis / complications
  • Venous Thrombosis / diagnosis*
  • Venous Thrombosis / diagnostic imaging

Substances

  • Contrast Media
  • Gadolinium DTPA