Neural induction

Curr Opin Genet Dev. 2000 Aug;10(4):357-62. doi: 10.1016/s0959-437x(00)00096-4.

Abstract

Development of neural fates from ectoderm is accompanied by the blockage of BMP signals at both protein and mRNA levels. Recent work has employed zebrafish, chick and mouse in addition to amphibians as models. Genetics has supplemented experimental embryology in enriching the understanding of the mechanism of neural induction and in posing new questions.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Bone Morphogenetic Proteins / antagonists & inhibitors
  • Cytoskeletal Proteins / metabolism
  • Ectoderm / physiology
  • Embryonic Induction / physiology*
  • Mesoderm / physiology
  • Mice
  • Organizers, Embryonic / physiology
  • Proto-Oncogene Proteins / metabolism
  • Signal Transduction / physiology*
  • Trans-Activators*
  • Wnt Proteins
  • Zebrafish Proteins*
  • beta Catenin

Substances

  • Bone Morphogenetic Proteins
  • CTNNB1 protein, mouse
  • Cytoskeletal Proteins
  • Proto-Oncogene Proteins
  • Trans-Activators
  • Wnt Proteins
  • Zebrafish Proteins
  • beta Catenin
  • wnt8b protein, zebrafish