Highly Stereoselective and Efficient Hydrosilylation of Terminal Alkynes Catalyzed by

Y Na; S Chang

doi:10.1021/ol0059697

Highly Stereoselective and Efficient Hydrosilylation of Terminal Alkynes Catalyzed by

Org Lett. 2000 Jun 29;2(13):1887-1889. doi: 10.1021/ol0059697.

Authors

Y Na¹, S Chang

Affiliation

¹ Department of Chemistry, Ewha Womans University, Seoul 120-750, Korea.

PMID: 10891183
DOI: 10.1021/ol0059697

Abstract

With [RuCl(2)(p-cymene)](2) as a catalyst, extremely high regio- and stereoselectivity was observed in the hydrosilylation reaction of various terminal alkynes under mild conditions to afford beta-(Z)-vinylsilanes in excellent yields. A dramatic directing effect was also observed when alkynes having a hydroxyl group at the beta position to the triple bond were employed as a substrate, and in these cases regioisomeric alpha-vinylsilanes were generated with excellent selectivity.