Bladder squamous cell carcinoma biomarkers derived from proteomics

Electrophoresis. 2000 Jun;21(11):2115-21. doi: 10.1002/1522-2683(20000601)21:11<2115::AID-ELPS2115>3.0.CO;2-K.

Abstract

Proteomics provide powerful technology for analyzing the expression levels of thousands of proteins simultaneously both in health and disease. Here, we review proteomic strategies that we have developed to identify metaplastic lesions in bladder squamous cell carcinomas as well as biomarkers in the urine for follow-up studies of squamous cell carcinoma (SCC)-bearing patients.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers, Tumor / urine*
  • Carcinoma, Squamous Cell / metabolism*
  • Carcinoma, Squamous Cell / pathology
  • Humans
  • Proteome*
  • Urinary Bladder Neoplasms / metabolism*
  • Urinary Bladder Neoplasms / pathology

Substances

  • Biomarkers, Tumor
  • Proteome