Abstract
In 45 sustained responders to interferon alfa and ribavirin, we found long-lasting elimination of hepatitis C virus RNA from serum and liver, together with histopathological improvement, suggesting complete recovery from chronic hepatitis C.
MeSH terms
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Alanine Transaminase / blood
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Antiviral Agents / therapeutic use*
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Biopsy
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Chronic Disease
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Drug Therapy, Combination
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Female
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Hepacivirus / genetics
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Hepacivirus / isolation & purification
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Hepatitis C / diagnosis
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Hepatitis C / drug therapy*
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Humans
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Interferon-alpha / therapeutic use*
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Liver / enzymology
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Liver / pathology
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Liver / virology
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Male
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Middle Aged
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Polymerase Chain Reaction
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Predictive Value of Tests
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RNA, Viral / blood
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Ribavirin / therapeutic use*
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Treatment Outcome
Substances
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Antiviral Agents
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Interferon-alpha
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RNA, Viral
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Ribavirin
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Alanine Transaminase