Genetic analysis of sliding motility in Mycobacterium smegmatis

J Bacteriol. 2000 Aug;182(15):4348-51. doi: 10.1128/jb.182.15.4348-4351.2000.

Abstract

A screen for nonsliding mutants of Mycobacterium smegmatis yielded 20 mutants with transposon insertions in the mps gene, which is involved in glycopeptidolipid biosynthesis. One mutant had an insertion in a gene predicted to encode a membrane transport protein. All mutants lacked glycopeptidolipids and were unable to form biofilms on polyvinyl chloride.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biofilms
  • Carrier Proteins / genetics*
  • Chemotaxis / genetics*
  • DNA Transposable Elements
  • Membrane Proteins / chemistry
  • Membrane Proteins / isolation & purification
  • Molecular Sequence Data
  • Mycobacterium smegmatis / genetics*
  • Open Reading Frames
  • Polyvinyl Chloride

Substances

  • Carrier Proteins
  • DNA Transposable Elements
  • Membrane Proteins
  • Polyvinyl Chloride

Associated data

  • GENBANK/AF271635