Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vps33b

Cytogenet Cell Genet. 2000;89(1-2):92-5. doi: 10.1159/000015571.

Abstract

We have identified VPS33B, the human ortholog of rat Vps33b. VPS33B encodes a transcript of 2482 nt with an ORF of 617 amino acids and a predicted protein size of 70.6 kDa. VPS33B contains a Sec-1 domain shared with a family of proteins involved in protein sorting and vesicular trafficking. Enriched expression of VPS33B was observed in testis. VPS33B was positioned at chromosome 15q26.1 by radiation hybrid mapping.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Chromosome Mapping
  • Chromosomes, Human, Pair 15 / genetics*
  • Cloning, Molecular
  • Expressed Sequence Tags
  • Gene Expression Profiling
  • Humans
  • Hybrid Cells
  • Lod Score
  • Male
  • Membrane Proteins*
  • Molecular Sequence Data
  • Open Reading Frames / genetics
  • Protein Structure, Tertiary
  • Proteins / chemistry
  • Proteins / genetics*
  • RNA, Messenger / analysis
  • RNA, Messenger / genetics
  • Rats
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Sequence Tagged Sites
  • Testis / metabolism
  • Vesicular Transport Proteins

Substances

  • Membrane Proteins
  • Proteins
  • RNA, Messenger
  • VPS33B protein, human
  • Vesicular Transport Proteins

Associated data

  • GENBANK/AF201694