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. Jul-Aug 2000;95(4):591-4.
doi: 10.1590/s0074-02762000000400025.

Acidic Ribosomal Proteins and Histone H3 From Leishmania Present a High Rate of Divergence

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Acidic Ribosomal Proteins and Histone H3 From Leishmania Present a High Rate of Divergence

Y Montoya et al. Mem Inst Oswaldo Cruz. .
Free article

Abstract

Another additional peculiarity in Leishmania will be discussed about of the amino acid divergence rate of three structural proteins: acidic ribosomal P1 and P2b proteins, and histone H3 by using multiple sequence alignment and dendrograms. These structural proteins present a high rate of divergence regarding to their homologous protein in Trypanosoma cruzi. At this regard, L. (V.) peruviana P1 and T. cruzi P1 showed 57.4% of divergence rate. Likewise, L. (V.) braziliensis histone H3 and acidic ribosomal P2 protein exhibited 31.8% and 41.7% respectively of rate of divergence in comparison with their homologous in T. cruzi.

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