Heterosexual transmission of hepatitis C, hepatitis B, and HIV-1 in a sample of inner city women

Sex Transm Dis. 2000 Jul;27(6):338-42. doi: 10.1097/00007435-200007000-00007.


Background: To clarify the role of heterosexual transmission of hepatitis C virus (HCV) and to identify associated risk factors.

Goal: To compare risk factors with infection among women with HCV, HIV-1, and hepatitis B virus (HBV).

Study design: A cross-sectional study of the prevalence of HCV, HIV-1, and HBV in a sample of 599 sexually active, nontransfused, inner-city women with no evidence of intravenous drug use.

Results: The prevalence of HCV was 1.6%, compared with 2.0% for HIV-1 and 18.8% for HBV; 75% of women infected with HCV were also infected with HIV-1 or HBV (P < 0.001). Women engaging in very high-risk sexual behavior were 14.2 times more likely to have HCV than other women (95% CI, 1.8-642.5).

Conclusions: The epidemic of HCV may be facilitated by high-risk sexual behavior. The relatively high prevalence of HCV suggests the need for more widespread screening among inner-city females.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Cross-Sectional Studies
  • Female
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • HIV-1*
  • Hepatitis B / epidemiology*
  • Hepatitis B / transmission
  • Hepatitis C / epidemiology*
  • Hepatitis C / transmission
  • Heterosexuality*
  • Humans
  • Middle Aged
  • New York City / epidemiology
  • Prevalence
  • Risk Factors
  • Surveys and Questionnaires
  • Urban Health
  • Women's Health