Use of the intubating laryngeal mask airway: are muscle relaxants necessary?

Anesthesiology. 2000 Aug;93(2):340-5. doi: 10.1097/00000542-200008000-00010.


Background: The intubating laryngeal mask airway (ILMA) is designed to facilitate blind tracheal intubation. The effect of a muscle relaxant on the ability to perform tracheal intubation through the ILMA device has not been previously evaluated. This randomized, double-blind, placebo-controlled study was designed to evaluate rocuronium, 0.2 or 0.4 mg/kg administered intravenously, on the success rate and incidence of complications associated with ILMA-assisted tracheal intubation.

Methods: A total of 75 healthy patients were induced with propofol 2 mg/kg and fentanyl 1 microg/kg intravenously. After insertion of the ILMA device, patients were administered either saline, rocuronium 0.2 mg/kg, or rocuronium 0.4 mg/kg in a total volume of 5 ml. At 90 s after administration of the study drug, tracheal intubation was attempted using a disposable polyvinyl tube. If unsuccessful, a reusable silicone tube was tried. In addition to recording the time and number of attempts required to secure the airway, the incidence of complications during placement of the tracheal tube and removal of the ILMA were noted.

Results: Tracheal intubation was successful in 76-96% of the patients. The overall success rates and times required to secure the airway were similar in all three treatment groups. The high-dose rocuronium group experienced less patient movement (8 vs. 28 and 48%) and coughing (12 vs. 20 and 52%) than the low-dose rocuronium and saline groups, respectively. Use of rocuronium was also associated with a dose-related decrease in the requirement for supplemental bolus doses of propofol during intubation and removal of the ILMA device.

Conclusions: Use of rocuronium did not significantly improve the success rate in performing tracheal intubation through the ILMA. However, it produced dose-related decreases in coughing and movement after tracheal intubation and reduced difficulties associated with removal of the ILMA device.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Androstanols / administration & dosage*
  • Androstanols / pharmacology
  • Anesthesia, Inhalation*
  • Anesthetics, Intravenous*
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Female
  • Fentanyl*
  • Hemodynamics / drug effects
  • Humans
  • Intubation, Intratracheal / methods*
  • Laryngeal Masks*
  • Male
  • Neuromuscular Nondepolarizing Agents / administration & dosage*
  • Neuromuscular Nondepolarizing Agents / pharmacology
  • Propofol*
  • Rocuronium


  • Androstanols
  • Anesthetics, Intravenous
  • Neuromuscular Nondepolarizing Agents
  • Fentanyl
  • Rocuronium
  • Propofol