Recurrent triploidy of maternal origin

Prenat Diagn. 2000 Jul;20(7):561-3. doi: 10.1002/1097-0223(200007)20:7<561::aid-pd875>;2-1.


We report the occurrence of triploid preimplantation embryos following in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in a woman with two previously-identified triploid conceptuses which spontaneously underwent fetal demise at 10 and 23 weeks' gestation. An error in maternal meiosis II is proposed as the most likely cause.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Habitual / etiology*
  • Adult
  • Blastocyst / physiology
  • Cytogenetics
  • Female
  • Fertilization in Vitro
  • Humans
  • In Situ Hybridization, Fluorescence
  • Meiosis
  • Nondisjunction, Genetic*
  • Oogenesis / genetics*
  • Polyploidy*
  • Pregnancy
  • Preimplantation Diagnosis*