Abstract
A series of N-(1-phenylethyl)-5-phenyl-imidazole-2-amines was prepared using solution-phase, parallel synthesis and evaluated for Na+/K+ ATPase inhibition.
MeSH terms
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Amines / chemical synthesis*
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Amines / chemistry
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Amines / pharmacology
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Animals
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Dogs
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Enzyme Inhibitors / chemical synthesis*
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / pharmacology
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Imidazoles / chemical synthesis*
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Imidazoles / chemistry
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Imidazoles / pharmacology
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Indicators and Reagents
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Kinetics
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Molecular Conformation
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Molecular Structure
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Myocardium / enzymology
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Sarcolemma / enzymology
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Sodium-Potassium-Exchanging ATPase / antagonists & inhibitors*
Substances
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Amines
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Enzyme Inhibitors
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Imidazoles
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Indicators and Reagents
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Sodium-Potassium-Exchanging ATPase