CT-guided percutaneous fibrin glue therapy of cerebrospinal fluid leaks in the spine after surgery

AJR Am J Roentgenol. 2000 Aug;175(2):443-6. doi: 10.2214/ajr.175.2.1750443.


Objective: The objective of this study is to assess CT-guided percutaneous injection of fibrin glue for the management of cerebrospinal fluid leaks within the spine.

Conclusion: Percutaneous CT-guided placement of fibrin glue can provide a treatment option for postoperative cerebrospinal fluid leaks, potentially allowing a major surgical procedure to be avoided. However, the complication of aseptic meningitis may occasionally result from this procedure.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Cerebrospinal Fluid*
  • Female
  • Fibrin Tissue Adhesive*
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / therapy*
  • Spinal Diseases / therapy*
  • Tissue Adhesives*
  • Tomography, X-Ray Computed


  • Fibrin Tissue Adhesive
  • Tissue Adhesives