Orbital involvement as the initial manifestation of sarcoidosis: magnetic resonance imaging findings

J Neuroimaging. 2000 Jul;10(3):180-3. doi: 10.1111/jon2000103180.


A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diagnosis, Differential
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Orbit / pathology
  • Orbital Diseases / diagnosis*
  • Sarcoidosis / diagnosis*