Fractals and cancer

Cancer Res. 2000 Jul 15;60(14):3683-8.

Abstract

Recent studies have shown that fractal geometry, a vocabulary of irregular shapes, can be useful for describing the pathological architecture of tumors and, perhaps more surprisingly, for yielding insights into the mechanisms of tumor growth and angiogenesis that complement those obtained by modern molecular methods. This article outlines the basic methods of fractal geometry and discusses the value and limitations of applying this new tool to cancer research.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Drug Delivery Systems
  • Fractals*
  • Humans
  • Hypoxia
  • Models, Biological*
  • Models, Theoretical*
  • Neoplasms / drug therapy
  • Neoplasms / pathology*
  • Neovascularization, Pathologic*