Colonic masses: detection with MR colonography

Radiology. 2000 Aug;216(2):383-8. doi: 10.1148/radiology.216.2.r00au11383.


Purpose: To assess magnetic resonance (MR) colonography as a method for detection of colorectal masses, with conventional colonoscopy as the reference standard.

Materials and methods: MR colonography was performed in 132 patients referred for colonoscopy because of the possible presence of a mass. After rectal filling with a gadopentetate dimeglumine and water enema, T1-weighted three-dimensional gradient-echo MR studies were acquired with the patient in the prone and supine positions. Water-sensitive single-shot fast spin-echo MR images were also obtained. Surface-rendered virtual endoscopic endoluminal views, orthogonal sections in three planes, and water-sensitive MR images were interactively assessed for presence of colorectal masses by two radiologists.

Results: MR colonography was well tolerated without sedation or analgesia. MR image quality was sufficient for diagnosis in 127 (96%) patients. Most small (</=5-mm-diameter) masses were overlooked at MR colonography, but 19 of 31 6-10-mm lesions and 26 of 27 large (>10-mm) lesions were correctly identified. For these large masses, MR colonography had a sensitivity of 93%, specificity of 99%, positive predictive value of 92%, and negative predictive value of 98% for detection of masses.

Conclusion: MR colonography is a promising modality for help in detecting colorectal mass lesions larger than 10 mm in diameter.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Rectal
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Colonic Neoplasms / diagnosis*
  • Colonoscopy
  • Contrast Media / administration & dosage
  • Enema
  • Female
  • Gadolinium DTPA / administration & dosage
  • Humans
  • Image Enhancement / methods
  • Image Processing, Computer-Assisted / methods
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prone Position
  • Sensitivity and Specificity
  • Supine Position
  • User-Computer Interface
  • Water


  • Contrast Media
  • Water
  • Gadolinium DTPA