Diffusion- and perfusion-weighted MRI in a patient with a prolonged reversible ischaemic neurological deficit

Neuroradiology. 2000 Jun;42(6):444-7. doi: 10.1007/s002340000303.


We report acute and follow-up diffusion- and perfusion-weighted MRI (DWI, PWI) findings in a patient with a prolonged reversible ischaemic neurological deficit. PWI 12 h after the patient was last seen to be without symptoms revealed a large perfusion deficit in the left posterior MCA territory with a relatively inconspicuous and much smaller abnormality on DWI. Follow-up showed resolution of abnormalities on both DWI and PWI, and conventional MRI was normal, apart from a very slight abnormality, visible only on FLAIR images, at the centre of the initially DWI-positive region. These findings demonstrate the utility of PWI when be used in combination with DWI to investigate the pathophysiology of transient ischemic syndromes.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aphasia, Wernicke / diagnosis
  • Cerebral Cortex / blood supply
  • Cerebral Cortex / pathology
  • Diffusion
  • Dominance, Cerebral / physiology
  • Follow-Up Studies
  • Humans
  • Image Enhancement*
  • Ischemic Attack, Transient / diagnosis*
  • Magnetic Resonance Imaging*
  • Male
  • Neurologic Examination*
  • Paresis / diagnosis
  • Posterior Cerebral Artery / pathology
  • Regional Blood Flow / physiology