Review
doi: 10.1016/s0367-326x(00)00176-3.
Grapefruit: the last decade acquisitions
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- PMID: 10930710
- DOI: 10.1016/s0367-326x(00)00176-3
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Review
Grapefruit: the last decade acquisitions
Fitoterapia.
2000 Aug.
Abstract
This review reports the last decade acquisitions on grapefruit. New coumarins and limonoids were isolated and characterised. The bioavailability of many drugs was tested with grapefruit juice (GJ) coadministration; the inhibition on cytochrome P450 seems due to a synergic action between flavonoids and coumarins. Antimicrobial, antifeeding, insecticidal, and antitumour activities were also reported.
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