Increased need for medical interventions in infants with velocardiofacial (deletion 22q11) syndrome

R J Hopkin; E K Schorry; M Bofinger; H M Saal

doi:10.1067/mpd.2000.108272

Increased need for medical interventions in infants with velocardiofacial (deletion 22q11) syndrome

J Pediatr. 2000 Aug;137(2):247-9. doi: 10.1067/mpd.2000.108272.

Authors

R J Hopkin¹, E K Schorry, M Bofinger, H M Saal

Affiliation

¹ Division of Human Genetics and the Craniofacial Center, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

PMID: 10931419
DOI: 10.1067/mpd.2000.108272

Abstract

Ten of 12 patients diagnosed with deletion 22q11.2 in infancy required a total of 26 hospitalizations during their first year of life. After heart disease, feeding and respiratory problems were the most frequent reasons for intervention.

MeSH terms

Abnormalities, Multiple / epidemiology
Abnormalities, Multiple / genetics
Abnormalities, Multiple / therapy*
Chromosome Deletion*
Chromosomes, Human, Pair 22*
Disease Management*
Feeding Behavior
Female
Heart Defects, Congenital / epidemiology
Heart Defects, Congenital / genetics
Heart Defects, Congenital / therapy*
Hospitalization / statistics & numerical data
Humans
Infant
Infant, Newborn
Male
Ohio / epidemiology
Respiratory Tract Infections / epidemiology
Retrospective Studies
Sucking Behavior