Control of action as mediated by the human frontal lobe

Exp Brain Res. 2000 Jul;133(1):71-80. doi: 10.1007/s002210000402.


Conscious control of action involves the voluntary initiation and the continuous adjustment of motor activity. Neuroimaging data provide evidence that the plan for a movement is developed with respect to the behavioral context in prefrontal cortex, while the synergies of a motor program are coded by premotor cortex and the specific movement parameters by the motor cortex. It is suggested that the initiational aspects of conscious motor activity are implemented in a medial system of information flow and the integrative aspects in a lateral system of the human frontal lobe.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Motor Cortex / physiology*
  • Movement / physiology*
  • Prefrontal Cortex / physiology*
  • Volition / physiology*