Some tenets pertaining to electrospray ionization mass spectrometry

J Mass Spectrom. 2000 Jul;35(7):763-72. doi: 10.1002/1096-9888(200007)35:7<763::AID-JMS16>3.0.CO;2-#.


The field of electrospray ionization mass spectrometry is reviewed with emphasis placed upon advances in the elucidation of fundamental mechanistic aspects of the ionization process that have been reported over the past 10 years. The analytical consequences of these findings are also examined. Eight central conclusions or 'tenets' are presented, as deduced from the body of work contained in 80 references.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Mass Spectrometry / methods*
  • Proteins / chemistry


  • Proteins