Reactivation of varicella-zoster virus in delayed facial palsy after dental treatment and oro-facial surgery

J Med Virol. 2000 Sep;62(1):42-5.

Abstract

In rare cases, acute peripheral facial palsy occurs several days after dental treatment and oro-facial surgery. Surgical procedures have been known to trigger reactivation of varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1). The present study examined eight patients who exhibited delayed facial palsy after dental treatment or oro-facial surgery. Ramsay Hunt syndrome was diagnosed in three patients and varicella-zoster virus (VZV) reactivation without zoster lesions (zoster sine herpete) was diagnosed in three patients either by PCR or serological assay. Therefore, VZV reactivation was detected in 75% (6 of 8) of patients who exhibited delayed facial palsy after dental or oro-facial treatment. The results suggest that VZV reactivation is a major cause of delayed facial palsy after dental treatment or oro-facial surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • DNA, Viral / analysis
  • Facial Paralysis / diagnosis*
  • Facial Paralysis / virology
  • Female
  • Herpes Zoster Oticus / diagnosis*
  • Herpes Zoster Oticus / virology
  • Herpesvirus 1, Human / growth & development*
  • Herpesvirus 3, Human / growth & development*
  • Humans
  • Male
  • Middle Aged
  • Oral Surgical Procedures / adverse effects*
  • Polymerase Chain Reaction
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / virology
  • Saliva / virology
  • Time Factors
  • Tooth Diseases / therapy
  • Virus Activation
  • Virus Latency

Substances

  • DNA, Viral