Seasonal variation in cryptogenic and noncryptogenic hemoptysis hospitalizations in France

Chest. 2000 Aug;118(2):440-4. doi: 10.1378/chest.118.2.440.


Study objective: To determine the potential role of seasonality in hospitalizations for cryptogenic and noncryptogenic hemoptysis in the French population.

Design: Retrospective analysis of hospital discharge data from a National Register.

Setting: All 29 French university hospitals, between July 1, 1994, and June 30, 1997.

Patients: Two thousand six hundred seventy-seven and 3,672 adult hospitalizations for cryptogenic and other hemoptysis, respectively.

Measurements: Cumulative monthly averages were determined, expressed as the percentage above or below the average monthly value during the entire study period.

Results: The distribution of cumulative monthly hospitalizations for cryptogenic hemoptysis peaked in March (32% above the average) and was lowest in summer (30% below the average; p < 0.001). Hospitalizations for noncryptogenic hemoptysis followed a similar seasonal pattern (p < 0. 001). In the 16- to 34-year-old individuals, cryptogenic hemoptysis, compared with noncryptogenic hemoptysis, showed a higher incidence with a larger seasonal amplitude (p < 0.001).

Conclusions: A better understanding of the fundamental pathophysiologic mechanisms underlying this respiratory and hemorrhagic condition may be helpful in developing preventive measures, especially in patients with a risk of recurrence.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Diagnosis, Differential
  • Female
  • France / epidemiology
  • Hemoptysis / diagnosis
  • Hemoptysis / epidemiology*
  • Hemoptysis / etiology*
  • Hospitalization / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Registries / statistics & numerical data
  • Retrospective Studies
  • Seasons*
  • Sex Distribution