Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes

Am J Hematol. 2000 Sep;65(1):50-5. doi: 10.1002/1096-8652(200009)65:1<50::aid-ajh9>;2-5.


Thrombotic thrombocytopenic purpura pathologically consists of a thrombotic microangiopathy that classically spares lung tissues. We describe a case of TTP that presented as a pulmonary-renal syndrome. In reviewing the international literature, pulmonary involvement is not as rare as once was thought, and the diagnosis of TTP should be considered in the differential diagnosis of pulmonary-renal syndromes.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Diagnosis, Differential
  • Dyspnea / complications
  • Fatal Outcome
  • Hemolytic-Uremic Syndrome / complications*
  • Hemolytic-Uremic Syndrome / diagnosis
  • Hemolytic-Uremic Syndrome / pathology
  • Humans
  • Kidney Diseases / complications*
  • Lung Diseases / complications*
  • Male
  • Middle Aged
  • Purpura, Thrombotic Thrombocytopenic / complications*
  • Purpura, Thrombotic Thrombocytopenic / diagnosis
  • Renal Dialysis
  • Syndrome