Narciclasine: an antitumour alkaloid which blocks peptide bond formation by eukaryotic ribosomes

FEBS Lett. 1975 Apr 1;52(2):236-9. doi: 10.1016/0014-5793(75)80813-1.
No abstract available

MeSH terms

  • Acyltransferases / metabolism*
  • Alkaloids / pharmacology*
  • Animals
  • Antineoplastic Agents / pharmacology*
  • Blood Proteins / biosynthesis*
  • Peptide Chain Elongation, Translational / drug effects
  • Peptide Elongation Factors
  • Phenylalanine
  • Polyribosomes / drug effects
  • Polyribosomes / metabolism
  • Protein Biosynthesis / drug effects*
  • RNA, Transfer / metabolism
  • Rabbits
  • Reticulocytes / metabolism
  • Ribosomes / drug effects
  • Ribosomes / metabolism*
  • Saccharomyces cerevisiae / metabolism

Substances

  • Alkaloids
  • Antineoplastic Agents
  • Blood Proteins
  • Peptide Elongation Factors
  • Phenylalanine
  • RNA, Transfer
  • Acyltransferases