Gender differences in the EEG of abstinent cocaine abusers

Neuropsychobiology. 2000;42(2):93-8. doi: 10.1159/000026678.

Abstract

Gender differences in the EEG were explored in cocaine-abusing individuals not seeking treatment. Twenty currently abstinent cocaine-abusing females aged 21-41 were studied. Their cocaine use history was matched to 20 currently abstinent cocaine-abusing males. Twelve female and 20 male non-drug-abusing individuals served as a control group. Resting eyes closed EEG was recorded from 8 leads. The males who used cocaine had elevated EEG beta (p<0.0125) and reduced alpha (p<0.0125) when compared to the cocaine-abusing females and control subjects. These findings suggest that the EEG of cocaine-abusing women may be more normal than that of cocaine-abusing men. Such gender-specific differences for cocaine-abusing populations may require gender-specific treatment to improve outcome.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Cocaine-Related Disorders / physiopathology*
  • Electroencephalography / drug effects*
  • Female
  • Humans
  • Male
  • Psychiatric Status Rating Scales
  • Sex Characteristics
  • Substance Withdrawal Syndrome / physiopathology*
  • Substance Withdrawal Syndrome / psychology