Isolated elevation of serum alkaline phosphatase level in an uncomplicated pregnancy: a case report

Am J Obstet Gynecol. 2000 Aug;183(2):505-6. doi: 10.1067/mob.2000.105841.


Serum level of alkaline phosphatase of placental origin was increased >10-fold in a 28-year-old pregnant woman. Repeated abdominal ultrasonographic scans yielded negative results for hepatobiliary disease. After delivery of a healthy baby, the placenta showed no major pathologic characteristics, and the alkaline phosphatase level returned to the reference range.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alkaline Phosphatase / blood*
  • Alkaline Phosphatase / metabolism
  • Female
  • Humans
  • Isoenzymes / blood
  • Placenta / enzymology
  • Pregnancy / blood*
  • Pregnancy Trimester, Third


  • Isoenzymes
  • Alkaline Phosphatase