Activation of the innate immune system by CpG oligodeoxynucleotides: immunoprotective activity and safety

Springer Semin Immunopathol. 2000;22(1-2):173-83. doi: 10.1007/s002810050027.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Adjuvants, Immunologic* / toxicity
  • Animals
  • Antibody Formation / drug effects
  • Bacterial Vaccines / immunology
  • Bacterial Vaccines / toxicity
  • Clinical Trials as Topic
  • CpG Islands / immunology*
  • Cytokines / biosynthesis*
  • DNA, Bacterial / immunology*
  • DNA, Bacterial / pharmacology
  • DNA, Bacterial / toxicity
  • Drug Evaluation, Preclinical
  • Francisella tularensis / immunology
  • Galactosamine / toxicity
  • Humans
  • Immunity, Innate / immunology*
  • Immunoglobulin M / biosynthesis*
  • Infection Control
  • Lipopolysaccharides / toxicity
  • Listeria monocytogenes / immunology
  • Listeriosis / prevention & control
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C3H
  • Mice, Inbred C57BL
  • Oligodeoxyribonucleotides / chemical synthesis
  • Oligodeoxyribonucleotides / immunology
  • Oligodeoxyribonucleotides / pharmacology
  • Safety
  • Tularemia / prevention & control
  • Vaccines, DNA / immunology
  • Vaccines, DNA / toxicity
  • Vaccines, Synthetic / immunology
  • Vaccines, Synthetic / toxicity

Substances

  • Adjuvants, Immunologic
  • Bacterial Vaccines
  • Cytokines
  • DNA, Bacterial
  • Immunoglobulin M
  • Lipopolysaccharides
  • Oligodeoxyribonucleotides
  • Vaccines, DNA
  • Vaccines, Synthetic
  • Galactosamine