Clinical observations of the treatment of canine perianal fistulas with topical tacrolimus in 10 dogs

B S Misseghers; A G Binnington; K A Mathews

Clinical observations of the treatment of canine perianal fistulas with topical tacrolimus in 10 dogs

Can Vet J. 2000 Aug;41(8):623-7.

Authors

B S Misseghers¹, A G Binnington, K A Mathews

Affiliation

¹ Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Ontario.

PMID: 10945128
PMCID: PMC1476229

Abstract

Tacrolimus ointment, a potent immunosuppressive medication, was evaluated for efficacy in the treatment of perianal fistulas in dogs. Ten dogs with perianal fistulas were treated with topical tacrolimus ointment once to twice daily for 16 weeks. Full healing of the fistulas occurred in 50% and was noticeably improved in 90% of dogs.

Publication types

Clinical Trial

MeSH terms

Administration, Topical
Animals
Dog Diseases / drug therapy*
Dog Diseases / pathology
Dogs
Female
Immunosuppressive Agents / administration & dosage*
Immunosuppressive Agents / pharmacology
Immunosuppressive Agents / therapeutic use
Male
Rectal Fistula / drug therapy
Rectal Fistula / veterinary*
Tacrolimus / administration & dosage*
Tacrolimus / pharmacology
Tacrolimus / therapeutic use
Treatment Outcome

Substances

Immunosuppressive Agents
Tacrolimus