Changing trends in genital herpes simplex virus infection in Bergen, Norway

Acta Obstet Gynecol Scand. 2000 Aug;79(8):693-6.


Aim of study: To document the proportion of each herpes simplex virus (HSV) type in genital HSV infection and changes over time during a 10 year period.

Design: Retrospective comparative study in sexually transmitted disease (STD) patients with genital HSV infection at the outpatient clinic for STD, Haukeland Hospital, Bergen, Norway.

Results: HSV-2 was the major cause during the 80's, whereas HSV-1 constitutes a greater part of the cases during the 90's, especially in female patients and in the younger age groups with primary or initial disease, where HSV-1 is the causative viral type in up to 70-90% of the cases.

Conclusion: The documented change from HSV-2 towards HSV-1 in cases of genital HSV infection may have implications as to prognosis, future usefulness of vaccines, present and future usefulness of new type-specific serological tests.

MeSH terms

  • Adult
  • Age Factors
  • Female
  • Herpes Genitalis / epidemiology*
  • Herpes Genitalis / virology
  • Herpesvirus 1, Human / pathogenicity*
  • Herpesvirus 2, Human / pathogenicity*
  • Humans
  • Incidence
  • Male
  • Norway / epidemiology