Urinary incontinence: an unrecognised adverse effect with donepezil

Lancet. 2000 Aug 12;356(9229):568. doi: 10.1016/S0140-6736(00)02588-5.

Abstract

Donepezil has been licensed for use in Japan to improve cognitive function since 1999. Among 94 patients with probable Alzheimer's disease who we treated with donepezil, seven patients developed urinary incontinence, although this event was transient in most patients.

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / drug therapy
  • Donepezil
  • Female
  • Humans
  • Indans / adverse effects*
  • Indans / therapeutic use
  • Male
  • Nootropic Agents / adverse effects*
  • Nootropic Agents / therapeutic use
  • Piperidines / adverse effects*
  • Piperidines / therapeutic use
  • Urinary Incontinence / chemically induced*

Substances

  • Indans
  • Nootropic Agents
  • Piperidines
  • Donepezil