Intra-arterial infusion of Solcoseryl: a clinical trial of a method of treatment for pre-gangrene of the lower limb

Br J Surg. 1975 May;62(5):337-9. doi: 10.1002/bjs.1800620502.

Abstract

A randomized double blind trial of the drug Solcoseryl given by intra-arterial infusion was carried out on 57 patients with pre-gangrene of the lower limb. A sequential analysis was carried out and the trial stopped when the results showed a statistically significant result in favour of the active drug.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Actihaemyl / administration & dosage
  • Actihaemyl / therapeutic use*
  • Aged
  • Arteriosclerosis / complications
  • Clinical Trials as Topic
  • Female
  • Gangrene / drug therapy*
  • Gangrene / etiology
  • Humans
  • Infusions, Parenteral
  • Injections, Intra-Arterial
  • Leg* / surgery
  • Male
  • Placebos
  • Tissue Extracts / therapeutic use*

Substances

  • Placebos
  • Tissue Extracts
  • Actihaemyl