Chemokines in Inflammation and Immunity

Immunol Today. 2000 Sep;21(9):418-20. doi: 10.1016/s0167-5699(00)01672-8.

Abstract

Since the discovery of interleukin 8 (IL-8), about 50 chemokines have been characterized. Originally, they were considered as inducible mediators of inflammation, but in recent years, several chemokines have been identified that are expressed constitutively and function in the physiological traffic and homing of leukocytes.

MeSH terms

  • Animals
  • Chemokines / physiology*
  • Hematopoiesis
  • Humans
  • Immunity*
  • Inflammation / etiology*
  • Lymphocytes / physiology

Substances

  • Chemokines