Viral mechanisms of immune evasion

Immunol Today. 2000 Sep;21(9):447-55. doi: 10.1016/s0167-5699(00)01699-6.


During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus-host interaction networks to understand viral pathogenesis, and could lead to new anti-viral strategies and the ability to exploit viral functions as tools in medicine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Apoptosis
  • Chemokines / physiology
  • Cytokines / physiology
  • Histocompatibility Antigens / physiology
  • Humans
  • Immune Tolerance
  • Interferons / physiology
  • T-Lymphocytes, Cytotoxic / immunology
  • Virus Diseases / immunology*


  • Chemokines
  • Cytokines
  • Histocompatibility Antigens
  • Interferons