Perinatal complications associated with maternal tobacco use

Semin Neonatol. 2000 Aug;5(3):231-41. doi: 10.1053/siny.2000.0025.


The use of tobacco products by pregnant women is associated with placenta previa, abruptio placentae, premature rupture of the membranes, preterm birth, intrauterine growth restriction and sudden infant death syndrome. Approximately 15-20% of women smoke during pregnancy. It has been suggested that smoking is responsible for 15% of all preterm births, 20-30% of all infants of low birthweight, and a 150% increase in overall perinatal mortality. Cigarette smoking is one of the most important and modifiable risk factors associated with adverse perinatal outcomes.

Publication types

  • Review

MeSH terms

  • Abruptio Placentae / etiology
  • Female
  • Fetal Growth Retardation / etiology*
  • Humans
  • Infant Mortality
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature*
  • Maternal Exposure
  • Obstetric Labor, Premature / etiology
  • Placenta Previa / etiology
  • Pregnancy
  • Pregnancy Complications / etiology*
  • Smoking / adverse effects*
  • Sudden Infant Death / etiology*
  • Tobacco Smoke Pollution / adverse effects


  • Tobacco Smoke Pollution