Evaluation of the iScreen digital screening system for amblyogenic factors

Can J Ophthalmol. 2000 Aug;35(5):258-62. doi: 10.1016/s0008-4182(00)80075-7.


Background: A digital photoscreener, the iScreen screening system, is now available to detect amblyogenic factors. We carried out a prospective study to evaluate the accuracy of the device in detecting anisometropia, significant refractive error, strabismus and opacities of the ocular media.

Methods: A total of 449 consecutive patients (median age 7 years) from a private pediatric ophthalmology practice underwent screening with the iScreen photoscreener operated by a minimally trained technician. The results were compared to the masked clinical examination of a pediatric ophthalmologist.

Results: The iScreen device had a sensitivity of 92.4%, specificity of 89.1%, positive predictive value of 94.1% and false-negative rate of 13.8%. Of the 21 patients with a false-negative result, 12 had myopia of less than -1.50 dioptres. High hyperopia was missed in two patients, high astigmatism in one, unequal cylindrical error in one and strabismus in five.

Interpretation: The iScreen digital photoscreener produced accurate and timely screening for potentially amblyogenic defects in the study population.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Amblyopia / diagnosis*
  • Amblyopia / etiology
  • Cataract / complications
  • Child
  • Child, Preschool
  • Computer Terminals
  • Diagnostic Techniques, Ophthalmological / instrumentation*
  • Electronic Data Processing / instrumentation*
  • Humans
  • Prospective Studies
  • Refractive Errors / complications
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Strabismus / complications
  • Visual Acuity