odd-skipped is expressed in multiple tissues during Drosophila embryogenesis

Mech Dev. 2000 Sep;96(2):233-6. doi: 10.1016/s0925-4773(00)00389-0.

Abstract

The odd-skipped (odd) gene encodes a zinc finger protein that represses other segmentation genes in the early Drosophila embryo. Though odd is initially expressed in a striped pattern that reflects its function within the segmentation hierarchy, it is also expressed in a variety of patterns during later stages of embryogenesis. To identify the cells and tissues that correspond to these latter patterns, we examined the distribution of the Odd protein at all embryonic stages. Our results indicate that Odd is a specific and persistent marker for subsets of cells in developing mesoderm, ectoderm, and neural tissue. We conclude that Odd is a useful tool for studying cell specification, cell migrations and morphogenetic movements during organogenesis of the heart, gut and central nervous system.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Central Nervous System / embryology
  • Central Nervous System / metabolism
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / metabolism
  • Digestive System / embryology
  • Digestive System / metabolism
  • Drosophila / embryology*
  • Drosophila / genetics*
  • Drosophila / metabolism
  • Drosophila Proteins*
  • Ectoderm / metabolism
  • Gene Expression Regulation, Developmental
  • Genes, Insect*
  • Insect Proteins / genetics*
  • Insect Proteins / metabolism
  • Kidney / embryology
  • Kidney / metabolism
  • Tissue Distribution
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism

Substances

  • DNA-Binding Proteins
  • Drosophila Proteins
  • Insect Proteins
  • Transcription Factors
  • odd protein, Drosophila