Nonpenetrating deep sclerectomy versus trabeculectomy in bilateral primary open-angle glaucoma

Ophthalmology. 2000 Sep;107(9):1671-4. doi: 10.1016/s0161-6420(00)00263-3.


Objective: To establish the efficacy and safety of nonpenetrating deep sclerectomy versus trabeculectomy in primary open-angle glaucoma.

Design: Prospective randomized trial.

Participants: Thirty-nine patients (78 eyes) with bilateral primary open angle glaucoma were included in the study.

Intervention: Eyes were randomly assigned to receive deep sclerectomy in one eye and trabeculectomy in the other eye.

Main outcome measures: Mean intraocular pressure (IOP), postoperative medications, visual acuity, success rate, and complications.

Results: At 12 months, mean IOP reduction was 12.3 +/- 4.2 (sclerectomy) versus 14.1 +/- 6.4 mmHg (trabeculectomy) (P = 0.15), and an IOP </= 21 mmHg was achieved in 36 (92.3%) and 37 eyes (94.9%) (P = 0.9), respectively. Complications included three (7.7%) flat/shallow anterior chambers and one (2.6%) hypotony (trabeculectomy), whereas internal iris incarceration was encountered in two eyes (5.1%) (sclerectomy).

Conclusions: Deep sclerectomy may provide comparable IOP reduction with fewer complications in management of primary open angle glaucoma.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Female
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Postoperative Complications
  • Safety
  • Sclerostomy / methods*
  • Trabeculectomy / methods*
  • Treatment Outcome
  • Visual Acuity