Hypothyroidism and primary open-angle glaucoma

Ophthalmologica. 2000 Sep-Oct;214(5):347-9. doi: 10.1159/000027518.

Abstract

Objective: To test if there is an association between hypothyroidism and primary open-angle glaucoma (POAG) and the utility of routine study of thyroid function in these patients.

Methods: The study was conducted in a case-control fashion. Seventy-five consecutive patients with a previous diagnosis of POAG and 75 control patients were prospectively evaluated for hypothyroidism. The levels of thyroid-stimulating hormone and free thyroxin were measured.

Results: Hypothyroidism was revealed in only 2 patients with previous diagnosis of POAG (2.67%) and 3 patients of the control group (4%).

Conclusions: As we have not been able to demonstrate the previously reported relationship between hypothyroidism and POAG, we cannot recommend the systematic screening for hypothyroidism in patients with POAG.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Case-Control Studies
  • Female
  • Glaucoma, Open-Angle / blood
  • Glaucoma, Open-Angle / complications*
  • Glaucoma, Open-Angle / epidemiology
  • Humans
  • Hypothyroidism / blood
  • Hypothyroidism / complications*
  • Hypothyroidism / epidemiology
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Prevalence
  • Prospective Studies
  • Spain / epidemiology
  • Thyrotropin / blood
  • Thyroxine / blood

Substances

  • Biomarkers
  • Thyrotropin
  • Thyroxine