The biology of inherited cancer

Semin Cancer Biol. 2000 Aug;10(4):251-4. doi: 10.1006/scbi.2000.0324.


This issue of Cancer Biology is focused on inherited cancer. In this short introduction to the topic we give a brief overview and list genes and the corresponding inherited cancer syndromes. We discuss the basic mechanisms of inherited cancer and the clinical implication of predictive genetic testing for cancer.

Publication types

  • Review

MeSH terms

  • Disease Susceptibility
  • Genetic Testing
  • Humans
  • Neoplasms / genetics*
  • Neoplastic Syndromes, Hereditary / genetics*
  • Pedigree
  • Risk Factors