DNA polymorphism in the genus Brucella

Microbes Infect. 2000 Jul;2(9):1089-100. doi: 10.1016/s1286-4579(00)01263-6.


The genus Brucella has been described as consisting of six species, three of them including several biovars, which display a high degree of DNA homology by DNA-DNA hybridization. However, DNA polymorphism able to differentiate the six Brucella species and some of their biovars has been shown to exist. This work reviews the DNA variability in the genus Brucella and discusses the relationships between its members according to this genetic variability and a proposal for their evolution based on genetic diversity of the omp2 locus.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacterial Outer Membrane Proteins / chemistry
  • Bacterial Outer Membrane Proteins / genetics
  • Base Sequence
  • Biological Evolution
  • Brucella / classification
  • Brucella / genetics*
  • DNA Transposable Elements / genetics
  • DNA, Bacterial / genetics*
  • Genome, Bacterial
  • Molecular Sequence Data
  • Phylogeny
  • Polymorphism, Genetic
  • Sequence Alignment
  • Species Specificity
  • Whales


  • Bacterial Outer Membrane Proteins
  • DNA Transposable Elements
  • DNA, Bacterial
  • Omp2 protein, bacteria