The authors tested a bee-hive product propolis as a drug to treat patients operated for goitre, patients with wounds and ulcerations difficult to heal and patients with non-specific rectal inflammation. They also tested the effectiveness of propolis as supplementary means in eradicating treatment of Helicobacter pylori. It was found that the drug was tolerated very well, practically had no side-effects and was highly effective. Preparations of propolis can be successfully used in surgery.