A Fusobacterium mortiferum strain produces a bacteriocin-like substance(s) inhibiting Salmonella enteritidis

Lett Appl Microbiol. 2000 Aug;31(2):115-7. doi: 10.1046/j.1365-2672.2000.00774.x.


Seven strictly anaerobic strains showing anti-Salmonella enteritidis activity were isolated from poultry caecal contents. Among them, the most inhibitory one, a strain of Fusobacterium mortiferum, called FM1025, was selected. Biochemical tests, showing the proteinaceous structure of the antagonist(s) produced, indicated that the strain Fus. mortiferum FM1025 synthesized (a) bacteriocin-like compound(s) active against Salm. enteritidis. Among the other strains tested, both Gram-negative and Gram-positive bacteria were inhibited. These preliminary results suggested the important role of the Fusobacterium strains against pathogenic bacteria among the intestinal flora.

MeSH terms

  • Animals
  • Bacteriocins / biosynthesis
  • Bacteriocins / pharmacology*
  • Cecum / microbiology
  • Fusobacterium / metabolism*
  • Poultry / microbiology
  • Salmonella enteritidis / drug effects*
  • Salmonella enteritidis / growth & development


  • Bacteriocins