Quantitative RT-PCR for CYP3A4 mRNA in human peripheral lymphocytes: induction of CYP3A4 in lymphocytes and in liver by rifampicin

Pharmacogenetics. 2000 Aug;10(6):571-5. doi: 10.1097/00008571-200008000-00011.

Authors

T Nakamoto¹, I Hase, S Imaoka, T Hiroi, Y Oda, A Asada, Y Funae

Affiliation

¹ Department of Anesthesiology, Osaka City Kita Citizen's Hospital, Osaka, Japan.

PMID: 10975612
DOI: 10.1097/00008571-200008000-00011

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Base Sequence
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System / biosynthesis
Cytochrome P-450 Enzyme System / genetics*
DNA Primers
Enzyme Induction
Humans
Liver / drug effects*
Liver / enzymology
Lymphocytes / drug effects*
Lymphocytes / enzymology
Mixed Function Oxygenases / biosynthesis
Mixed Function Oxygenases / genetics*
RNA, Messenger / genetics*
Rats
Reverse Transcriptase Polymerase Chain Reaction
Rifampin / pharmacology*

Substances

DNA Primers
RNA, Messenger
Cytochrome P-450 Enzyme System
Mixed Function Oxygenases
CYP3A protein, human
Cytochrome P-450 CYP3A
CYP3A4 protein, human
Rifampin