Quantitative RT-PCR for CYP3A4 mRNA in human peripheral lymphocytes: induction of CYP3A4 in lymphocytes and in liver by rifampicin

Pharmacogenetics. 2000 Aug;10(6):571-5. doi: 10.1097/00008571-200008000-00011.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System / biosynthesis
  • Cytochrome P-450 Enzyme System / genetics*
  • DNA Primers
  • Enzyme Induction
  • Humans
  • Liver / drug effects*
  • Liver / enzymology
  • Lymphocytes / drug effects*
  • Lymphocytes / enzymology
  • Mixed Function Oxygenases / biosynthesis
  • Mixed Function Oxygenases / genetics*
  • RNA, Messenger / genetics*
  • Rats
  • Reverse Transcriptase Polymerase Chain Reaction
  • Rifampin / pharmacology*

Substances

  • DNA Primers
  • RNA, Messenger
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • CYP3A protein, human
  • Cytochrome P-450 CYP3A
  • CYP3A4 protein, human
  • Rifampin