Assessing the environmental risk of novel technological systems and of the European Union (EU) policies supporting them and regulating their implementation requires good understanding of (i) the pressure on the environment posed by the large-scale use of new technology, and (ii) the vulnerability of the receptor of this pressure. Generic life-cycle assessments (LCAs) provide exhaustive accounting of environmental pressure, yet they do not take into account the vulnerability of the receiving ecosystem. Generic studies of technology externalities fail to produce conclusions on the impacts in a certain area of the systems envisaged due to lack of site-specific information. The combined use of generic (LCA) and spatially referenced data offers new opportunities for comprehensively analysing the environmental impact of novel technologies. A novel information fusion methodology is suggested. Example applications are presented herein focusing on the evaluation of renewable energy technologies as an example of the implementation of meso-scale LCA for integrated environmental risk assessment of EU technology policies.