STAT signalling in cell proliferation and in development

Curr Opin Genet Dev. 2000 Oct;10(5):503-7. doi: 10.1016/s0959-437x(00)00119-2.

Abstract

Recent advances in STAT signalling research include a better understanding of the roles of mammalian STAT proteins in cell proliferation and apoptosis, and of non-mammalian STAT proteins in morphogenesis. Two different ways in which STAT signalling pathways can interface with Smad signalling pathways significantly increasing combinatorial signalling possibilities, have also been described.

Publication types

  • Review

MeSH terms

  • Animals
  • Apoptosis / physiology
  • Cell Division / physiology*
  • Gene Expression Regulation, Developmental
  • Humans
  • Signal Transduction*
  • Trans-Activators / physiology*

Substances

  • Trans-Activators