Vascular Developmental Biology: Getting Nervous

Curr Opin Genet Dev. 2000 Oct;10(5):536-42. doi: 10.1016/s0959-437x(00)00124-6.

Abstract

First described in the developing nervous system, Semaphorin III/Neuropilin, Ephrin/Eph, and Delta/Notch signaling relays have now been implicated in the elaboration of the blood vessel network during embryogenesis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Glycoproteins / physiology
  • Humans
  • Membrane Proteins / physiology
  • Neovascularization, Physiologic / physiology*
  • Nerve Tissue Proteins / physiology
  • Nervous System / embryology
  • Neuropilin-1
  • Receptors, Notch
  • Semaphorin-3A
  • Signal Transduction

Substances

  • Glycoproteins
  • Membrane Proteins
  • Nerve Tissue Proteins
  • Receptors, Notch
  • Semaphorin-3A
  • Neuropilin-1